| 학회 |
한국화학공학회 |
| 학술대회 |
2004년 가을 (10/29 ~ 10/30, 호서대학교(아산캠퍼스)) |
| 권호 |
10권 2호, p.1441 |
| 발표분야 |
분리기술 |
| 제목 |
The effect of molecular weight on Poly (L-lactic acid) in the supercritical antisolvent precipitation and fractionation using Rapid Expansion Solvent System |
| 초록 |
The main purpose of this research was to find the effect of molecular weight on particle size in the Aerosol Solvent Extraction System (ASES) using supercritical CO2 as an anti-solvent. In addition, Rapid Expansion of Supercritical Solution (RESS) technique was also used. The particle formation model was tested with poly(L-lactic acid) (L-PLA) which are different in molecular weight from 50,000 to 220,000. In ASES process, the experiments were performed under conditions such as pressure (100bar), temperature (36ºC), initial concentration (0.5wt%) and solution flow rate (0.3㎖/min). It was found that ASES gave fine particle size (70-1600nm) with a narrow size distribution by spraying methylene chloride solution including L-PLA varied from molecular weight. RESS conducted the fractionation experiment on the products made by ASES. Supercritical HCFC-22 was used as a solvent in RESS process. The particle size and morphology were measured using Scanning Election Microscopy (SEM), Particle Size Analyzer (PSA) and Gel Permeation Chromatography (GPC). |
| 저자 |
정헌섭1, 이창하2, 임종성3, 이윤우4
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| 소속 |
1한국과학기술(연), 2연세대, 3서강대, 4서울대 |
| 키워드 |
Supercritical fluids; Molecular weight of L-PLA; ASES; RESS
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| E-Mail |
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| 원문파일 |
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