Chemistry Letters, Vol.30, No.7, 738-739, 2001
Aminoisocyanides in multicomponent reactions (MCRs): A facile synthesis of substituted 3(5H)-pyrrolin-2-ones via a Dimroth-type rearrangement
The 1,3-dipolar species generated from diisopropyl aminoisocyanide and dimethyl acetylenedicarboxylate (DMAD) is trapped with aldehydes affording substituted 3(5H)-pyrrolin-2-ones presumably via a Dimroth-type rearrangement of the initially formed furanone hydrazones in good yields.