화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Polymer(Korea), Vol.29, No.3, 314-319, May, 2005
Export Citation
새로운 지방족 디올/디카복실산계 생분해성 폴리에스테르 및 가수분해 특성
New Aliphatic Diol/Dicarboxylic Acid Based Biodegradable Polyesters and Their in-vitro Degradations
강태곤1, 2, 한양규1, 2, †
  • 1한양대학교 화학과
  • 2한국과학기술원 기능성고분자신소재연구센타
Tae-Gon Kang1, 2, and Yang-Kyoo Han1, 2, †
  • 1Department of Chemistry, Hanyang University, Seoul 133-791, Korea
  • 2Korea Center for Advanced Functional Polymers, KAIST, Daejeon 305-701, Korea
E-mail:
초록
촉매인 stannous octoate 존재 하에서 글리콜리드를 이관능성 개시제인 1,4-butanediol, 1,6-hexanediol, 1,4-cyclohexanediol, 1,4-cyclohexanedimethanol과 반응시켜 4가지 종류의 새로운 지방족 디올을 합성하였다. 이들 새로운 디올과 succinic acid, adipic acid, 혹은 suberic acid와 titanium(IV) isopropoxide 촉매하에서 170, 190, 또는 220 ℃에서 축합중합시켜 분자구조가 규칙적으로 배열된 새로운 지방족 폴리에스테르와 무질서한 구조를 갖는 폴리에스테르를 각각 얻었다. 이들 지방족 폴리에스테르들의 유리전이온도(Tg)는 -40에서 30 ℃ 사이였다. 또한 170 ℃에서 제조된 분자구조가 규칙적으로 배열된 폴리에스테르가 높은 온도에서 합성된 구조가 무질서한 폴리에스테르들보다 Tg가 5-10 ℃ 정도 높았다. 체외분해 실험 결과, 분자구조가 규칙적으로 배열된 폴리에스테르가 불규칙한 중합체보다 완충용액 속에서 가수분해속도가 느렸다.
Four kinds of new aliphatic diols were synthesized by the ring opening reaction of glycolide with 1,4-butanediol, 1,6-hexanediol, 1,4-cyclohexanediol, or 1,4-cyclohexanedimethanol, a difunctional initiator, in the presence of stannous octoate catalyst. The resulting diols were melt-polymerized with succinic acid, adipic acid, or suberic acid at 170, 190, or 220 ℃ to produce new sequentially ordered aliphatic polyesters and their corresponding polyesters with random structure. Their glass transition temperatures (Tg) ranged from -40 to 30 ℃. The sequentially ordered polyesters prepared at 170 ℃ had higher Tg of 5 to 10 ℃ than the polyesters with random structure produced at higher temperature. From in-vitro degradation test, the sequentially ordered polyesters was slower in the rate of hydrolysis in a buffer solution than the polymers with random molecular structure.
Keywords:sequentially ordered aliphatic diol;biodegradable polyesters;transesterification;in-vitro degradation;degradation rate
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