TNO, a Dutch organisation for contract research, is and has been involved in numerous process intensification projects in close collaboration with national and international process industries. TNO has different facilities available to fulfil the demands of intensification projects. Depending on the focus of a project, a multidisciplinary team conducts experimental research, feasibility studies, process modelling, process design, pilot research and/or E-evaluations (economics, environment, energy). In this conference paper practical cases are described concerning novel processing techniques as well as novel reactors. (C) 2003 Society of Chemical Industry.