화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Journal of Industrial and Engineering Chemistry, Vol.9, No.1, 45-50, January, 2003
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Self-Association between Nano-sized Bilayer and Amphiphilic Polymer
Sang Yoon Kang, Moon Ki Park1, and Hee-Tae Jung†
  • Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science & Technology, Daejeon 305-701, Korea
  • 1Department of Environmental Engineering, Kyungsan University, Kyungsan 712-715, Korea
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The membrane bending elastic modulus and microstructure were estimated for the vesicles with and without the addition of polymer-surfactant macromolecules by cryogenic transmission electron microscopy (cryo-TEM) and small angle neutron scattering (SANS). The mixture of cetyltrimethylammonium tosylate (CTAT) and sodium dodecylbenzensulfonate (SDBS) self-assembles into vesicle phase. In order to examine the effect of polymer addition, Poly (ethylene glycol)-dimyristoylphosphatidylethanolamine is used as the component of added macromolecule. The bilayer bending rigidity is evaluated as 0.5 kBT from the size distribution obtained by the image analysis of cryo-TEM regardless of polymer addition. However, it is observed from SANS curves that the width of size distribution is reduced as the amount of polymer is increased because of enhanced bilayer asymmetry after polymer's penetration into membrane. Therefore the mechanism of incorporating polymer into bilayer is understood as that the hydrophobic part of polymer is anchored into the membrane of vesicle following the adsorption onto the surface of vesicle from the aqueous phase.
Keywords:self-assembly;vesicle bilayer;amphiphilic polymer;stiffness
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