혼합물 실험 계획법을 활용한 세정용 계면활성제 혼합물 조성의 최적화

송마리아; 진병석; Maria Song; Byung Suk Jin

Applied Chemistry for Engineering, Vol.32, No.5, 574-580, October, 2021

DOI10.14478/ace.2021.1072 Export Citation

혼합물 실험 계획법을 활용한 세정용 계면활성제 혼합물 조성의 최적화

Optimization of Surfactant Mixture Composition for Cleansing Using Mixture Experiment Design

송마리아, 진병석^†

동덕여자대학교 보건향장학과

Maria Song, and Byung Suk Jin^†

Department of health and cosmetics, Dongduk Women’s University, Seoul 02748, Korea

E-mail:

초록

최고 품질의 클렌징 제품 개발을 위해서 계면활성제 혼합물 조성의 최적화를 시도하였다. 사전실험을 통해 세정력, 기포형성력, 오염률에서 각각 우수한 특성을 나타내는 계면활성제 3종 sodium cocoyl alaninate (SCoA), cocamidopropyl betaine (CPB), decyl glucoside (DG)을 선정하였다. 계면활성제 혼합물의 심플렉스 중심 설계 배열에 따른 실험을 수행하고, 실험에서 얻어진 데이터를 가지고 회귀분석을 실시하였다. 통계적으로 유의미한 반응 표면 모델식을 구하고, 세 개의 반응변수의 동시 최적화 과정을 통해 계면활성제 혼합물의 최적 조성은 SCoA (0.22), CPB (0.78), DG (0.00)으로 구해졌다.

The main goal of this study was to find an optimal surfactant mixture composition for the development of the best performing cleansing products. Three different surfactants including sodium cocoyl alaninate (SCoA), cocamidopropyl betaine (CPB), and decyl glucoside (DG) were selected, which showed excellent properties in detergency, foaming height, and contamination rate through preliminary experiments. The experiments by simplex centroid design matrix for surfactant mixtures were performed, and the regression analysis was conducted with the experimental data. Surface response model equations, which is statistically significant (p < 0.05), were obtained. The optimal composition of the surfactant mixture was also determined as SCoA (0.22), CPB (0.78), and DG(0.00) from simultaneous optimization of three response variables.

Keywords:Mixture experiment design;Optimal mixture composition;Surfactant;Cleansing;Detergency

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[2] Sandhu RK, Kaur A, Kaur P, Rajput JK, Khullar P, Bakshi MS, J. Mol. Liq., 336, 116305 (2021)

[3] Krishnakumar V, Elansezhian R, Mater. Today:Proceedings, (2021).

[4] Koner S, Pal A, Adak A, Desalination, 276(1-3), 142 (2011)

[5] Tamjidi S, Moghadas BK, Esmaeili H, Khoo FS, Gholami G, Ghasemi M, Process Saf. Environ. Prot., 148, 775 (2021)

[6] Babajanzadeh B, Sherizadeh S, Ranji H, Open Access J. Sci., 3(3), 94 (2019)

[7] Abdellahi B, Bois R, Golonu S, et al., Tetrahedron Lett., 74, 153113 (2021)

[8] Effendy I, Maribach HI, Contact Dermatitis, 33(4), 217 (1995)

[9] Holland PM, Rubingh DN, Mixed surfactant systems: an overview, 2-30 (1992).

[10] Bera A, Ojha K, Mandal A, J Surfactants Deterg, 16(4), 621 (2013)

[11] Jadidi N, Adib B, Malihi FB, J Surfactants Deterg, 16(1), 115 (2013)

[12] Zawala J, Wiertel-Pochopien A, Kowalczuk PB, Minerals, 10, 192 (2020)

[13] Chu HH, Yeo YS, Chuang KS, Polymer, 48(8), 2298 (2007)

[14] Mishra M, Muthuprasanna P, Parabhe KS, Rani PS, Satish IA, Ch IS, Arunachalam G, Shalini S, Int. J. Pharmtech Res, 1(4), 1354 (2009)

[15] Geng T, Zhang C, Jiang Y, Ju H, Wang Y, J. Mol. Liq., 232, 36 (2017)

[16] Huang J, Zhu L, Zeng G, Shi L, Shi Y, Yi K, Li X, Colloids Surf. A: Physicochem. Eng. Asp., 570, 81 (2019)

[17] Derringer G, Suich R, J. Qual. Technol., 12(4), 214 (1980)