화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Journal of Industrial and Engineering Chemistry, Vol.96, 109-120, April, 2021
DOI10.1016/j.jiec.2020.12.031  Export Citation
Insights into the major phenolic acids in Perilla frutescens obtained by a sustainable procedure
Yu-Chiao Yang1, 2, Chia-Sui Wang3, and Ming-Chi Wei3, †
  • 1Department and Graduate Institute of Pharmacology, Kaohsiung Medical University, Kaohsiung 80708, Taiwan
  • 2Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan
  • 3Department of Environmental Engineering & Science, Chia Nan University of Pharmacy and Science, Tainan 71710, Taiwan
E-mail:
This research was performed to evaluate the efficiency of ultrasound in obtaining the total extract, caffeic acid and rosmarinic acid from Perilla frutescens using supercritical CO2 (USCCO2) extraction. Compared with traditional heat-reflux, ultrasonic-assisted and SCCO2 extractions, the USCCO2 technique decreased the extraction duration (1.12-1.92 times) and the consumption of solvent (1.90-285.71 times) at lower extraction temperatures and obtained a higher yield from the plant matrix. Furthermore, a second-order kinetic model and Fick’s second diffusion model were implemented to ascertain the extraction rate constant, equilibrium concentration, initial extraction rate, effective diffusion coefficient, mass transfer coefficient, Biot number, equilibrium constant and thermodynamic parameters of the USCCO2 and SCCO2 dynamic extractions of rosmarinic acid from P. frutescens. These results provide valuable insights into the kinetic and mass transfer behaviors that occur during the USCCO2 and SCCO2 procedures and explain the reasons for the better extraction efficiency of the former procedure.
Keywords:Perilla frutescens;rosmarinic acid;ultrasound-assisted supercritical CO2;extraction;green procedure;Fick’s second diffusion model;thermodynamic parameters
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