화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Journal of Industrial and Engineering Chemistry, Vol.48, 202-211, April, 2017
DOI10.1016/j.jiec.2017.01.003  Export Citation
Isolation of triterpenic acid-rich extracts from Hedyotis corymbosa using ultrasound-assisted supercritical carbon dioxide extraction and determination of their
Ming-Chi Wei1, Show-Jen Hong2, and Yu-Chiao Yang2, 3, †
  • 1Department of Applied Geoinformatics, Chia Nan University of Pharmacy and Science, Tainan 71710, Taiwan
  • 2Department and Graduate Institute of Pharmacology, Kaohsiung Medical University, Kaohsiung 80708, Taiwan
  • 3Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan
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The present study investigated a green ultrasound-assisted supercritical carbon dioxide (USC-CO2) process for extracting oleanolic acid (OA) and ursolic acid (UA) from Hedyotis corymbosa. Chrastil, Bartle and Kumar and Johnston models were used to correlate the experimental fictitious solubility data. The overall average absolute relative deviation (AARD (%)) in solid solubility ranged from 3.632% to 6.529%, which indicates good agreement between the experimental fictitious solubility data and the modeled results. Using the correlation results, the total heat of solution and the enthalpies of vaporization and solvation for OA and UA in the USC-CO2 extraction process were also estimated.
Keywords:Hedyotis corymbosa;Oleanolic acid;Ursolic acid;Fictitious solubility;Ultrasound-assisted supercritical CO2;extraction
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