Country-specific determinants of intra-industry trade between the Czech Republic and its European Union trading partners in pharmaceutical products in 2004-2017 were evaluated. The Bayesian Model Averaging (BMA) method was used, where the bilateral intra-industry index, calcd. according to the Grubel-Lloyd formula, was adopted as the explained variable. The intensity of intra-industry trade in Czech-EU trade in pharmaceuticals were detd. by intensity of trade with particular EU countries, by the size of general government expenditure on health in the countries of trading partners and by the level of economic development of the trading partners.