화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Macromolecular Research, Vol.26, No.1, 48-53, January, 2018
DOI10.1007/s13233-018-6005-4  Export Citation
Synthesis and characterization of electrospun PU/PCL hybrid scaffolds
Gayeon Oh, Jeongwon Rho, Deuk Yong Lee†, Myung-Hyun Lee1, and Young-Zu Kim2
  • Departmnet of Biomedical Engineering, Daelim University, Anyang, Gyeonggi 13916, Korea
  • 1Energy and Environmental Division, Korea Institute of Ceramic Engineering and Technology, Jinju, Gyeongnam 52851, Korea
  • 2Vericom Co., Ltd., Anyang, Gyeonggi 14087, Korea
E-mail:
Polyurethane/poly(ε-caprolactone) (PU/PCL) scaffolds with various concentrations of PCL (0 to 40 wt%) were electrospun to evaluate the mechanical properties and the biocompatibility of the PU/PCL hybrid scaffolds. The 10 wt% PU/PCL scaffolds were chosen due to the absence of beads. The ultimate tensile strengths of 10 wt% PU and 15% PCL scaffolds were 8.0±1.3 MPa and 6.8±1.0 MPa. The tensile strength of PU/PCL scaffolds increased dramatically to 12.1±1.4 MPa when 10% PCL was added to PU. As the PCL content was raised to 20%, 30%, and 40%, the strength of PU/PCL scaffolds started to decrease to 8.9±1.1 MPa, 7.6±0.6 MPa, and 5.3±0.6 MPa, respectively. The highest strength was observed for the 90/10 PU/ PCL scaffolds and no cytotoxicity was detected.
Keywords:polyurethane(PU);poly(ε-caprolactone)(PCL);hybrid scaffold;electrospinning;mechanical property;cytotoxicity
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