Operation of a platinum-based diesel oxidation catalyst under lean conditions leads to the partial transformation of metallic Pt sites into platinum oxides (PtOx) with considerably lower NO oxidation rate. The varying NO2 yield depending on PtOx coverage significantly influences the performance of other devices following in a diesel exhaust aftertreatment line: particulate filter (soot oxidation) and SCR or LNT catalyst (NOx reduction). In this paper, we present a global kinetic model of a diesel oxidation catalyst, including PtOx formation induced by reactions with O-2 and NO2, PtOx reduction by CO, hydrocarbons and NO, and PtOx thermal decomposition, and use it to reveal the extent of NO2 yield variation in four standard driving cycles for passenger car emission tests: NEDC, FTP, US06 and SC03. During a single driving cycle, the NO2 yield decreases by 3-10% relative to the original level of the reduced catalyst. The PtOx formation is a slow process and stabilizes only after approximately four repeated driving cycles. The stabilized NO2 yield is 7-27% (relative) lower than with the reduced catalyst, depending mainly on the history of operating temperatures. The largest variation is observed around 250-300 degrees C. At lower temperatures, PtOx are partly reduced during CO and hydrocarbon peaks in the engine exhaust during dynamic operation. At higher temperatures, PtOx start to decompose and NO oxidation becomes limited by equilibrium.