Removal of Ag(I) and Cr(VI) by complexation-ultrafiltration, anionic polyacrylamide being the complexation agent, has been reported. Effects of operating variables such as initial metal ions concentration in feed, feed pH, polymer-to-metal ions ratio, and applied pressure on the removal of metal ions were studied at a constant feed flow rate of 15 L/min. Maximum rejection obtained were close to 100% for Ag(I) and 94% for Cr(VI) ions in single ion system; and for binary ions system it is 87% for Ag(I) and 76% for Cr(VI) ions. The membrane was characterized using the combined-film theory-Spiegler-Kedem (CFSK) model.