Recent rapidly growth in nanotechnolgies is promised novel benefits through the exploitation of their unique industrial and biomedical applications. In addition, these nanomaterials and nano-consumer products have increased in quantity per year, and thus their uncontrolled release into the environment is anticipated to grow dramatically in future. Many papers for cytotoxicity of nanomaterials have been already reported, and thus government supports has funded to various research topics for nanosafety. Herein, we analyzed the importance and performance of nanosafety researches and tried to show the research direction where we have to go.