| 학회 |
한국공업화학회 |
| 학술대회 |
2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
19권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Effects of protein stability on adsorption kinetics at biointerface |
| 초록 |
Protein adsorption exerts significant effects on the success of biomaterials since the adsorbed protein molecules determined cell adhesion and subsequent cellular responses, including spreading, mobility, proliferation, and differentiation. This study investigated the kinetic modeling of protein adsorption to silica surface using site-directed mutant proteins which possess different structural stability. The adsorption kinetic data was collected using in-situ ellipsometer. Competitive adsorption was analyzed using radioactive iodine (I125). Our result demonstrated that protein structural stability exert significant effects on adsorption behavior and less stable protein showed greater competitivity. |
| 저자 |
Le Thi Kim Tram, 이수희, 김주승, 김지혜, 이우걸, 정은진
|
| 소속 |
단국대 |
| 키워드 |
biointerface; protein; adsorption; stability
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| E-Mail |
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