화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2010년 가을 (10/27 ~ 10/29, 대전컨벤션센터)
권호 14권 2호
발표분야 나노
제목 Controlled self-assembly of macrocyclic peptides intoz α-helix-decorated nanorings and nanofibers
초록 α-Helix is an essential secondary structural motif in protein. Herein, we show a simple but effective supramolecular approach, in which multiple α-helix-coated artificial proteins can be constructed by the self-assembly simple peptides. Given that α-helix at the exterior of protein is one of the key mediators of biological recognition events, our design principle can provide a good starting point for developing artificial proteins that can modulate α-helix-mediated molecular recognition occurring in a multivalent fashion.
저자 정우진, 최성주, 한상헌, 배남석, 임용범
소속 연세대
키워드 α-helix; self-assembly
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