초록 |
α-Helix is an essential secondary structural motif in protein. Herein, we show a simple but effective supramolecular approach, in which multiple α-helix-coated artificial proteins can be constructed by the self-assembly simple peptides. Given that α-helix at the exterior of protein is one of the key mediators of biological recognition events, our design principle can provide a good starting point for developing artificial proteins that can modulate α-helix-mediated molecular recognition occurring in a multivalent fashion. |