| 학회 |
한국화학공학회 |
| 학술대회 |
2014년 가을 (10/22 ~ 10/24, 대전 DCC) |
| 권호 |
20권 2호, p.1577 |
| 발표분야 |
생물화공 |
| 제목 |
Electrospun Nanofiber/Hydrogel Composite Scaffolds for Cellular and Viral Delivery |
| 초록 |
Electrospinning has been shown as a versatile and efficient way to fabricate the nanofibrous structures. Although it has many advantages to be used in tissue engineering applications, to be used in actual medicinal practice, electrospun scaffolds have a critical disadvantage: they can only be fabricated into two-dimensional sheet-like shapes with small pore size. Based on previousy study investigating 3D moldable nanofibrous scaffolds, lubricating hydrogels and clay-like electrospun nanofibrous scaffolds were combined to fabricate the injectable electrospun scaffolds. The injectable scaffolds were able to be injected through the syringe and the fibrous structure and hydrogels were intact after injection. Thus, injected and aligned nanofibrous structure provided physical guidance for three dimensional and directional growth of the cells and injectability of the scaffolds is safe and patient-friendly. Nanofibrous scaffolds which can be injected through injection have a great potential to be employed as advanced tissue engineering scaffolds carrying and delivering cells and soluble factors. |
| 저자 |
이슬기림, 진규형, 김승현, 최우용, 정운룡, 장재형
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| 소속 |
연세대 |
| 키워드 |
Scaffolds; Electrospinning; Cell delivery; Human neural stem cells
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| E-Mail |
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| 원문파일 |
초록 보기 |
