| 초록 |
In this study, specific molecular recognition between vancomycin (VAN) conjugated 40~50nm gold nanoparticles (Au NPs) in sensor chips and oligo peptides mimicked from Vancomycin Resistant Enterococcus (VRE) wall membrane is employed as nanosensor based on Localized Surface Plasmon Resonance (LSPR) . Oligopeptides, which were anchored to 5nm Au NPs, having terminal D-Ala-D-Ala and D-Ala-D-Lac regions were compared to specific binding toward VAN conjugated nanosensor, respectively. Difference of LSPR characteristic in nanobiosensor was shown in absorbance intensity and wavelength shift between different terminal oligopeptides, D-Ala-D-Ala and D-Ala-D-Lac |
