| 초록 |
In 3D printing tubular structures for tissue engineering, direct printing methods are typically considered using thermoplastic polymers and hydrogels. In the case of printing by directly heating and extruding a thermoplastic polymer, there is a limitation of excessively high mechanical stiffness compared to the native soft tissues. In the case of hydrogels used in bioprinting methods including cells, on the contrary, they have too low stiffness and weak strength. In this presentation, we will introduce a polymer solution-based templating process that indirectly utilizes the 3D printing process. After 3D printing the sacrificial template using a water-soluble polymer, a polymer solution was dip-coated on the surface and the inner template was removed to produce a 3D customized flexible tubular structure. It was possible to further improve mechanical biocompatibility and cellular functionality by combining it with the particle leaching method and electrospinning method, respectively. |
