| 학회 | 한국고분자학회 |
| 학술대회 | 2003년 봄 (04/11 ~ 04/12, 연세대학교) |
| 권호 | 28권 1호, p.161 |
| 발표분야 | 기능성 고분자 |
| 제목 | pH에 민감한 계면활성제를 이용한 베시클 제조 및 특성연구 |
| 초록 | Several ion pair amphiphiles (IPA) that are composed of two positive parts (ammonium surfactants) and one negative part (dicarboxlyate surfactant) are prepared to test whether the IPA vesicles can sense the change in pH of surrounding solution and respond by reassembling their aggregation structures. Among IPA candidates, one with asymmetric chain length of positive parts showed high and reliable pH-sensitivity as compared to IPA with symmetric chain length, which can be utilized in switching-on of release of encapsulated fluorescence marker and design of pH-sensitive drug delivery vehicle. Reasons for such high pH-sensitivity are sought from combined physical properties such as turbidity, zeta potential, surface tension, and release rate of marker through the bilayer membrane. |
| 저자 | 정명훈;이태진;박정환;전병철;정용찬 |
| 소속 | 수원대 |
| 키워드 | 고분자; PH; Vesicle; Liposome |
