| 학회 |
한국재료학회 |
| 학술대회 |
2009년 가을 (11/05 ~ 11/06, 포항공과대학교) |
| 권호 |
15권 2호 |
| 발표분야 |
D. Health and Biological Materials(생체 및 의용재료) |
| 제목 |
Cell Growing Behavior on the Electrospun PVA/GE nanofiber mats. |
| 초록 |
Electrospinning of Polyvinyl alcohol (PVA), Gelatin (GE), and PVA/GE blend solutions in acetic acid were investigated to fabricate biodegradable for tissue engineering. The morphology of the electrospun nanofibers was investigated with a field emission scanning electron microscope. The fibers have average diameters in the range 50-150 nm. The miscibility of PVA/GE blend fibers was examined by differential scanning calorimetry. The PVA and GE were immiscible in the as-spun nanofibrous structure. X-ray diffraction (XRD) determined the crystallinity of the membrane and tensile strength for evaluation physical properties. An in vitro study of PVA/GE blend nanofibers was conducted. To assay the cytocompatibility and cell behavior on the PVA/GE blend nanofibrous scaffolds, cell attachment and spreading of fibroblasts seeded on the scaffolds were studied. Our results indicate that the PVA/GE blend nanofibrous matrix, particularly the one that contained 20% PVA and 80% GE could be a good candidate for tissue engineering scaffolds, because it has an excellent cell attachment and spreading for fibroblast cell. |
| 저자 |
Nguyen Thuy Ba Linh1, Thi-Hiep Nguyen2, Ho-Yeon Song3, Hun Mo Yang1, Young Ki Min2, Byong-Taek Lee3
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| 소속 |
1Department of Biomedical Engineering and Materials, 2School of Medicine, 3Soonchunhyang Univ. |
| 키워드 |
PVA; GE; Electrospinning; PVA/GE blend; Fibroblast cell
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| E-Mail |
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