| 학회 | 한국화학공학회 |
| 학술대회 | 2002년 봄 (04/26 ~ 04/27, 강원대학교) |
| 권호 | 8권 1호, p.1241 |
| 발표분야 | 생물화공 |
| 제목 | 유기상 효소반응을 이용한 메틸글루코시드 아크릴레이트 합성 |
| 초록 | Research on sugar esters synthesized from renewable agricultural resources has received keen attention with the prospect of the production of less pollutant molecules. Sugar esters constitute an interesting group of non-ionic, biocompatible and biodegradable surfactants, which are widely used in the cosmetic, pharmaceutical, detergent and food industries [1]. Recently, there has been a great interest in finding biodegradable surface active compounds to replace pollutant chemical surfactants. They can be enzymatically synthesized from renewable starting substrates, in mild reaction conditions [2]. Moreover, these enzymatic methods can be performed in less toxic solvents compared with those of chemical synthesis. Lipase has been often used in reactions for the formation of sugar esters due to a high regioselectivity and stereoselectivity [3,4], and these reactions lead to defined product usable without any hazards in the food, cosmetic and medical industries. Several researchers have investigated the lipase-catalyzed synthesis of sugar containing acrylic esters and biodegradable polymers due to their biomedical applicability [5,6,7]. Acrylic acid has a high hydrophilic characteristic due to its carboxylic group capable of esterifying with the hydroxyl group of sugars. Moreover, it has a vinyl group that can be polymerized. Therefore acrylic esters are expected to be used as monomers for sugar polymers having hydrophilicity and biocompatibility. The aim of this study was to investigate the esterification of carboxylic acid with β- methylglucoside using Candida antartica lipase, Novozym 435. The effects of reaction parameters such as enzyme amount, molar ratio of substrates, initial β-methylglucoside concentration and reaction temperature were also studied. |
| 저자 | 김지석, 박대원, 함승주, 김우식 |
| 소속 | 연세대 |
| 키워드 | esterification; lipase; β-methylglucoside; sugar ester |
| 원문파일 | 초록 보기 |
