| 초록 |
Rutin (R) exhibits a wide range of biological activities including anticarcinogenic, anti-inflammatory and antiviral actions. The purpose of this study is to investigate the effect of rutin concentrations (1 wt%, 3 wt%) on the antibacterial activity of poly(3-hydroxybutyrate-co-hydroxyvalerate) (PHBV) scaffolds. Antibacterial activity was evaluated by using Staphylococcus aureus and Klebsiella pneumoniae. Furthermore, the qualitative ingrowth of human KB epithelial cells was done to study in vitro cytotoxicity of the scaffolds. As the results, PHBV/R scaffolds completely inhibited the proliferation of Staphylococcus aureus and Klebsiella pneumoniae. The PHBV/R scaffolds used in this study did not show any cytotoxicity. |
