| 학회 | 한국고분자학회 |
| 학술대회 | 2005년 가을 (10/13 ~ 10/14, 제주 ICC) |
| 권호 | 30권 2호 |
| 발표분야 | 의료용 고분자 부문위원회 |
| 제목 | Poly(ε-caprolactone) and collagen based scaffolds for drug release |
| 초록 | A new biodegradable polymeric scaffold containing high molecular weight poly(ε-caprolatctone) (PCL) and collagen were prepared. These scaffolds were found to be soft, spongy and transparent in nature. To these scaffolds, anti-microbial drugs amikacin and gentamycin were incorporated separately to study their release profile from scaffolds. The amikacin and gentamycin release activity of these scaffolds with a fixed collagen content but different quantities of poly(ε-caprolatctone) (PCL) were studied during 1, 4, 24, 48 and 60 h by measuring the optical density at 257 and 255 nm amikacin and gentamycin, respectively. Acknowledgement This work was supported by the Regional Research Center Program of the Korean Ministry of Education & Human Resources Development through the Center for Health Care Technology Development, Chonbuk National University, Chonju, 561-756, Republic of Korea. |
| 저자 | 프라부1, Vijaya Ramesh2, 박종훈3, 김학용4, Nallasamy Dharmaraj1 |
| 소속 | 1전북대, 2Bio-Products Laboratory, 3Central Leather Research Insitute, 4India |
| 키워드 | poly(ε-caprolactone); collagen; scaffolds; amikacin; gentamycin |
