| 학회 | 한국공업화학회 |
| 학술대회 | 2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 | 19권 2호 |
| 발표분야 | 콜로이드계면화학_포스터 |
| 제목 | Study of Micelle's Dynamics with Nuclear Magnetic Resonance Spectroscopy |
| 초록 | Block copolymer micelles have been widely used in biomedical and cosmetic fields as delivery materials because of a specific targeting and delivering drugs / anti-aging components. In order to evaluate a performance of micelle, various Nuclear Magnetic Resonance(NMR) parameters such as chemical shifts, T1, T2 relaxation time and diffusion coefficient value which represent dynamic information of a micelle core part that is flexibility and mobility are studied. Herein, we researched micelles which are composed of diblock and triblock copolymer through a high resolution NMR that is powerful method in examining atomic level information. First of all, we investigated critical micelle concentrations(CMC) and thermo stability of core parts following a change of concentration and temperature respectively by using the NMR parameters. Then, stability differences of delivery fuctional part were confirmed in existence / nonexistence condition of lecithin which is an emulsifying agent. Additionally, with the preceding whole data, we evaluated a performance of micelles as delivery materals. |
| 저자 | 최익장, 정기진, 고혜지, 이영복, 공경현 |
| 소속 | 한양대 |
| 키워드 | Nuclear Magnetic Resonance Spectroscopy; Micelle dynamics |
