초록 |
Glass capillary device has been widely used in droplet microfluidics due to ease of assembly, organic solvent resistance, and 3D tapered geometry. However, production of monodisperse sub-50 µm double emulsions in these devices is challenging. In this work, we utilize 3D poly(dimethyl siloxane)(PDMS) device to produce monodisperse double emulsion droplets for cosmetic applications. We show that our device with spatial pattern in surface wettability allows robust production of double emulsion templated microcapsules for encapsulation and retention of TECA, a cosmetic ingredient with antioxidant activity. We further confirm the validity of this approach by demonstrating that monodisperse polymersomes with size below 50 µm can be produced for effective skin delivery. |