학회 |
한국재료학회 |
학술대회 |
2011년 가을 (10/27 ~ 10/29, 신라대학교) |
권호 |
17권 2호 |
발표분야 |
제 21회 신소재심포지엄-Electrospinning: Materials and Applications |
제목 |
Nanofibrous meshes promoting celular proliferation |
초록 |
Biomedical applications of electrospun nanofibrous meshes have been receive tremendous attentions because of their unique structures and versatilities as novel biomaterials. Incorporation of growth factors in fibrous meshes can be performed by surface-modification and encapsulation. Those growth factors stimulate differentiation and proliferation of specific types of cells and thus lead tissue regenerations of specific cell types. Topographical cues of electrospun nanofibrous meshes also increase differentiation of specific cell types according to alignments of fibrous structures. Wound healing treatments of diabetic ulcers were performed using nanofibrous meshes encapsulating multiple growth factors. Aligned nanofibrous meshes and those with random configuration were compared for differentiating mesenchymal stem cells into neuronal cells. Thus, nanofibrous meshes can be applied to novel drug delivery carriers and matrix for promoting cellular proliferation. |
저자 |
유혁상, 최지숙, 김혜성
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소속 |
강원대 |
키워드 |
nanofiber; wound helaing; differentiation; stem cell
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E-Mail |
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