| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 가을 (10/06 ~ 10/07, 김대중 컨벤션센터) |
| 권호 |
36권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Electro and pH-responsive transdermal drug delivery of PVA/PAAc/GO nanocomposite hydrogels |
| 초록 |
The poly(vinyl alcohol)/poly(acrylic acid)/graphite oxide (GO) nanocomposites were prepared by film casting method for electro and pH-responsive transdermal drug delivery system. The graphite was oxidized with acid for the improved dispersion in the hydrogel. The morphologies of nanocomposite hydrogels were investigated by scanning electron microscope. The dual electro and pH-dependent swelling and releasing properties of hydrogels were investigated in various buffer solutions under electric voltages applied. The electrical conductivities of PVA/PAAc/GO nanocomposite hydrogels were measured by surface resistance analyzer. The electro and pH-responsive transdermal drug delivery characteristics were studied based on the morphology, electrically modulated swelling, and drug releasing behaviors of the nanocomposite hydrogels. |
| 저자 |
정고운, 윤주미, 김형일
|
| 소속 |
충남대 |
| 키워드 |
Electro-responsive; pH-responsive; transdermal drug delivery
|
| E-Mail |
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