| 초록 |
Photo-responsive hydrogels are ideal candidates for applications in drug delivery systems due to their minimal invasiveness and potential for remote control. Therefore, many thermal-responsive hydrogels have been combined with photothermal agents. In this study, thermosensitive poly(N-isopropylamide-co-acrylic acid) was fabricated as a drug carrier and Prussian blue (PB) as a photothermal agent (microgel@PB). When microgel was irradiated with an 808 nm laser, PB could absorb NIR light and transform light into heat. Then, the heat was transferred to the thermal-responsive microgel, which caused the lower critical solution temperature phase transition. As a result, microgel@PB could release the drug by shrinking and able to apply as a potential druge delivery system in response to NIR light. |
