학회 |
한국고분자학회 |
학술대회 |
2010년 가을 (10/07 ~ 10/08, 대구 EXCO) |
권호 |
35권 2호 |
발표분야 |
의료용 고분자 |
제목 |
Preparation and Characterization of O-Carboxymethyl chitosan ion-complexed Ofloxacin for Drug delivery system |
초록 |
OCMCh-ofloxacin(OCMChOflo) was prepared by ion-complex with OCMCh and ofloxacin for drug delivery system. The physicochemcal characterisitcs of OCMChOflo was investigated by FT-IR, 1H NMR. Particle size distribution and zeta potential of the OCMChOflo was determined using dynamic light scattering technique. Transmission electron microscopy(TEM) was also used to observe the morphology of the OCMChOflo. For a molecular weight measurement used gel permeation chromatograph(GPC). The release behaviors of OCMChOflo from this proposed delivery system in phosphate-buffered saline (PBS) solution at 37 °C were studied by UV. |
저자 |
남정표, 김영민, 손동희, 박준규, 김원석, 최창용, 장미경, 나재운
|
소속 |
순천대 |
키워드 |
OCMCh; ofloxacin; OCMChOflo.;
|
E-Mail |
|