| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션) |
| 권호 |
20권 1호 |
| 발표분야 |
콜로이드계면화학_포스터 |
| 제목 |
Biomimetic Self-assembly of Porphyrin-conjugated Polyaspartamide in aqueous solution |
| 초록 |
Nano-sized self-assemblies with various morphologies are being extensively studied to use them in a variety of biological and industrial applications including targeted drug delivery. This study reports a novel strategy to prepare self-assemblies with high aspect ratio by varying of packing structure. We synthesized poly(2-hydroxyethyl aspartamide) (PHEA) grafted with porphyrins, which could form self-assemblies in an aqueous solution. Then, increasing the degree of substitution of porphyrins induced the structural transition to rod-like assemblies. This strategy to prepare polymer self-assemblies will serve to improve the efficiency of targeted delivery for a molecular optical and ultrasound imaging with various biomedical modalities. |
| 저자 |
조윤나, 한사라, 김희진, 조성우, 정재현
|
| 소속 |
숭실대 |
| 키워드 |
Polyaspartamide; Porphyrin; Self-assembly; Degree of substitution
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| E-Mail |
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