| 학회 |
한국공업화학회 |
| 학술대회 |
2022년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
26권 1호 |
| 발표분야 |
포스터-생체재료 |
| 제목 |
MXene-Functionalized PLCL/Collagen Nanofiber Matrices to Facilitate Spontaneous Myogenic Differentiation |
| 초록 |
Recently, MXene (Ti3C2TX ) has drawn increasing attention due to its fascinating physicochemical properties. Herein, MXene-functionalized poly(L-lactide-co-ε-caprolactone)/collagen (PLCL/Col/MXene) nanofiber matrices were fabricated via electrospinning and their potential as scaffolds for skeletal muscle tissue engineering was examined. FT-IR spectroscopy, SEM, AFM, and contact angle measurement were carried out to characterize the PLCL/Col/MXene nanofibers. It was found that the PLCL/Col/MXene nanofiber matrices promote the spontaneous myogenic differentiation of C2C12 myoblasts without hampering their growth. In conclusion, it is suggested that the topographical and biochemical advantages of the MXene-functionalized nanofibers can be a promising strategy for skeletal muscle tissue engineering and regeneration. |
| 저자 |
이석현1, 강문성1, 장희정1, 조효정1, 이종호2, 정승조1, 김봉주3, 한동욱1
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| 소속 |
1부산대, 2다안코리아, 3서울대 |
| 키워드 |
MXene; electrospinning; nanofibers; muscle tissue engineering
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| E-Mail |
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