| 학회 |
한국공업화학회 |
| 학술대회 |
2006년 봄 (05/12 ~ 05/13, 전북대학교) |
| 권호 |
10권 1호 |
| 발표분야 |
고분자 |
| 제목 |
Application of Thermosensitive Nanoparticles based on Poly(N-isopropylacrylamide-b-ε-caprolactone) and Poly(ethylene glycol-b-ε-caprolactone) |
| 초록 |
Thermosensitive nanoparticles were prepared by self assembly of two different poly(ε-caprolactone) based block copolymers of poly(N-isopropylacrylamide)-b-poly(ε-caprolactone) (PNP-PCL) and poly(ethylene glycol)-b-poly(ε-caprolactone) (PEG-PCL). The microscopic investigation of the mixed aggregates revealed that the critical aggregation concentration, the partition equilibrium constants of pyrene, and the aggregation number of PCL chain per one hydrophobic microdomain were varied by compositions of the mixed aggregates. Furthermore, the PNP-PCL containing mixed aggregates showed phase transition behavior, originated by coil to globule transition of PNP block upon heating. |
| 저자 |
최창용1, 채수영1, 장학수1, 장미경1, 조종수2, 나재운1
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| 소속 |
1순천대, 2서울대 |
| 키워드 |
Thermosensitivity; Drug delivery system
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| E-Mail |
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