| 학회 |
한국고분자학회 |
| 학술대회 |
2012년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
37권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Fabrication of PVA microspheres using freezing-thawing and gamma-irradiation |
| 초록 |
Poly(vinyl alcohol) (PVA) hydrogels are very attractive materials for biomedical application, as they have inherent non-toxicity, good biocompatibility and excellent physical properties. As shown through these properties, PVA hydrogels can also be used to fabricate particles for various uses such a drug delivery system, filter material and tissue engineering scaffolds. In this study, PVA hydrogel microspheres were prepared using a water-in-oil method with freezing-thawing cycles and radiation induced crosslinking. First, a PVA aqueous solution prepared at 90 ºC was added to silicone oil. The mixture was then dispersed to form water-in-oil emulsion using a probe type sonicator. Second, the dispersed mixture was crosslinked under freezing-thawing cycles and gamma-ray irradiation. Finally, its physicochemical properties were measured through SEM, FT-IR and degree of swelling. |
| 저자 |
조선영, 권희정, 신영민, 박종석, 정성인, 최종배, 박은지, 임종영, 노영창, 강필현, 임윤묵
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| 소속 |
한국원자력(연) |
| 키워드 |
Poly(vinyl alcohol); Microspheres; Freezing-thawing; Radiation crosslinking
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| E-Mail |
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