| 초록 |
Cyanoacrylates are single-part, solvent-free adhesives that form strong bonds on a wide variety of substrates. The rapidly polymerizing alkyl cyanoacrylates have been used as tissue adhesives and hemostatic agents because of their ability to adhere to moist tissue and skin. Cyanoacrylate tissue adhesives are expected to be potential for bonding the wounds as compared to the suture. Alkyl cyanoacrylates were synthesized by first making oligo(alkyl cyanoacrylate) through a condensation reaction of alkyl cyanoacrylates with paraformaldehyde, followed by a depolymerization of the prepolymer at an elevated temperature in an acidic atmosphere with a high vacuum. They have some side chains by introducing the different alkyl substituents. In this study, three kinds of octyl cyanoacrylates such as n-octyl, 2-octyl, and 2-ethylhexyl cyanoacrylates were directly prepared by a Knoevenagel reaction and then pyrolysis. The chemical structures of the obtained prepolymers and monomers were identified by 1H NMR and FTIR. In addition, their physical and mechanical properties were investigated. |
