| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 가을 (10/09 ~ 10/10, 일산킨텍스) |
| 권호 |
33권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Biological Affinity and Biodegradability of PPC |
| 초록 |
We investigated poly(propylene carbonate) (PPC) about bacterial and cell adhesion. PPC was synthesized by copolymerization of carbon dioxide (a global warming chemical) with propylene oxide. We also assessed the biocompatibility and biodegradability of the films in vivo, and their oxidative degradation in vitro. It was found that there was different adhesion characteristic of bacteria species to the smooth, hydrophobic PPC surface after 4 h incubation and no adhesion of human cell (HEp-2) due to the hydrophobicity and dimensional instability of the surface. In contrast, the PPC films showed good biocompatibility mouse subcutaneous environment. Moreover, the PPC films were found to degrade in the mouse subcutaneous environment but on the other hand it showed resistance to oxidative degradation in vitro. All results will be discussed with surface characteristics of the polymer. |
| 저자 |
김가희1, 이문호1, 김희수2, 김미희1, 정정운1
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| 소속 |
1포항공대, 2동국대 |
| 키워드 |
Poly(propylene carbonate); Bacterial adhesion; Cell adhesion; Biocompatibility; Biodegradability
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| E-Mail |
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