| 학회 |
한국공업화학회 |
| 학술대회 |
2008년 가을 (11/12 ~ 11/14, ICC 제주) |
| 권호 |
12권 2호 |
| 발표분야 |
고분자 |
| 제목 |
Controlled release of model drug from pH-sensitive hydrogel matrix containing temperature-sensitive microcapsules |
| 초록 |
A novel drug delivery system (DDS), which consists of poly(vinyl alcohol) (PVA)/poly(N-isopropylacrylamide) (PNIPAAm) hydrogel microspheres and poly(vinyl alcohol) (PVA)/poly (acrylic acid) hydrogel matrix, was developed for prolonged and sustained controlled release. Various amounts of PVA/PNIPAAm microspheres were incorporated physically into pH-sensitive PVA/PAAc hydrogel matrix. The effect of temperature and pH on the swelling ratio and the response kinetics was also investigated to understand the smart propertiesof the composite hydrogel systems. |
| 저자 |
윤주미, 김형일
|
| 소속 |
충남대 |
| 키워드 |
hydrogel; microcapsules; drug delivery system
|
| E-Mail |
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