| 학회 |
한국재료학회 |
| 학술대회 |
2010년 가을 (11/11 ~ 11/12, 무주리조트) |
| 권호 |
16권 2호 |
| 발표분야 |
D. Health and Biological Materials(생체 및 의용재료) |
| 제목 |
Fabrication of Hyaluronic acid-Gelatin/Biphasis Calcium Phosphate scaffold for bone tissue engineering application |
| 초록 |
In order to develop a proper scaffold for bone tissue engineering, a hyaluronic acid (HyA) – Gelatin (Gel) hydrogel and HyA-Gel hydrogel loaded in Biphasic Calcium Phosphate (BCP) were prepared. BCP scaffold was formed by sponge replica method with the compressive strength marked 1.3 MPa. The HyA-Gel hydrogel in their ratio of 15:85 was loaded in sponge BCP for the purpose of obtaining a biocompatibility and harder scaffold. An in vitro study of HyA-Gel hydrogel and HyA-Gel/BCP scaffold were conducted. To assay the cytocompatibility and cell behavior on the HyA-Gel hydrogel and HyA-Gel/BCP scaffold, cell attachment and spreading of osteoblast cell MG-63 seeded on the scaffolds were studied. Our results provide a novel and simple method to obtain an adequate scaffold for osteoblast cells and indicate that HyA-Gel hydrogel and HyA-Gel/BCP scaffold could be a good candidate for bone tissue engineering scaffolds, because it has an excellent cell attachment and spreading for MG-63cell. |
| 저자 |
Lee Hyun Ki1, Nguyen Thuy Ba Linh2, Min-Sung Kim3, Byong-Taek Lee4
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| 소속 |
1Department of Medical Science, 2Kyung Hee Univ., 3Department of Biomedical Eng. & Mater., 4School of Medicine |
| 키워드 |
Hyaluronic acid; Gelatin; BCP; MG-63; bone tissue engineering
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| E-Mail |
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