화학공학소재연구정보센터
학회 한국재료학회
학술대회 2009년 봄 (05/21 ~ 05/22, 무주리조트)
권호 15권 1호
발표분야 나노생체재료
제목 Influence of tailored degree of substitution on hyaluronic acid hydrogels properties
초록 Hyaluronic acid (HyA) concentration and molecular weight have been correlated with the development of certain pathological conditions and can be used as diagnostic markers for disease. HyA allowed attachment of a wide variety of cell types and connected a wide variety of growth factors. The properties of HyA hydrogels having a broad range of methacrylation are presented. Increasing solubility of glycidyl methacrylate (GM) in a co-solvent mixture during the methacrylation of HyA with GM was shown to produce photopolymerizable HyAGM conjugates with various degree of methacrylation. 1H NMR spectroscopy was used to verify the methacrylation reaction on HyA. These novel GMHA hydrogels are suitable for using in a variety of woundhealing applications.
저자 Nguyen Thuy Ba Linh1, Hun Mo Yang2, Young Ki Min3, Byong-Taek Lee4
소속 1Department of Biomedical Eng. & Mater., 2School of Medicine, 3Soonchunhyang Univ., 4Department of Physiology
키워드 hyaluronic acid; hydrogel; photopolymerization; tissue engineering
E-Mail