| 학회 |
한국고분자학회 |
| 학술대회 |
2014년 봄 (04/10 ~ 04/11, 대전 컨벤션센터) |
| 권호 |
39권 1호 |
| 발표분야 |
의료용 고분자 부문위원회(초청-영어발표/포스터-국문발표 가능) |
| 제목 |
Hydrophobization of Silk Fibroin Nanofiber Surfaces by Fluorocarbon Plasma Treatment to Regulate Cell Adhesion and Proliferation Behavior |
| 초록 |
Silk fibroin(SF) is widely used for tissue engineering scaffold because of their biocompatibility, biodegradability and non-toxicity. In this study, SF nanofibrous mats were fabricated by simple electrospinning method. Conformational change of SF was induced by water vapor treatment from random coil to ß-sheet structures determined by ATR-FTIR, 13C CP/MAS NMR. After CF4 gas plasma treatment, the surface property of SF nanofibrous mats was dramatically changed to hydrophobic determined by XPS and water contact angle measurement. We have investigated fibroblasts’ behavior on each CF4 gas plasma treated and untreated SF nanofibrous mats. Fibroblasts' viability on electrospun nanofibrous mats was determined by MTT assay. SF nanofibrous mats with extremely hydrophobic surface can be used as biomedical materials, especially for guided bone regeneration (GBR) membranes. |
| 저자 |
이민영1, 이재백1, 방수미1, 박원호2, 조동환1, 권오형1
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| 소속 |
1국립금오공과대, 2충남대 |
| 키워드 |
guided bone regeneration; Tissue engineering; silk fibroin; nanofiber; electrospinning; cell adhesion
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| E-Mail |
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