| 학회 |
한국공업화학회 |
| 학술대회 |
2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
19권 2호 |
| 발표분야 |
나노_포스터 |
| 제목 |
Carbon Nanotube/Tandem Antibody Nanoprobes for Multiplex Detection of proPSAs |
| 초록 |
Multiplex detection of prostate-specific antigen (PSA) and proPSA including [-2]proPSA, [-5]proPSA and [-7]proPSA in blood is considered to be a promising way to improve the accuracy of prostate cancer detection. We developed the nanoprobes producing strong resonance Raman scattering signals by controlling the orientation and density of tandem antibodies specific for proPSAs on single-walled carbon nanotubes (SWNTs), denoted SNA, for multiplex detection of PSA derivatives. The SNAs showed an enhanced binding affinity to the target molecules, and they were able to selectively detect [-2]proPSA, [-5]proPSA, and [-7]proPSA captured on the magnetic beads. |
| 저자 |
김종호, 박정현, 김만진, 임다빈, 전수지, 김혜인
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| 소속 |
한양대 |
| 키워드 |
Cabonnanotube; tandem antibody; proPSA detection; Nanoprobe; Multiplex detection
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| E-Mail |
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