| 학회 |
한국재료학회 |
| 학술대회 |
2013년 가을 (11/06 ~ 11/08, 제주롯데호텔) |
| 권호 |
19권 2호 |
| 발표분야 |
D. 바이오재료(Biomaterials) |
| 제목 |
Development of vasculogenic injectable hydrogel with growth factor for tissue engineering application |
| 초록 |
Recently, injectable hydrogels are promising substrates for tissue engineering applications. We have reported the biodegradable crosslinked injectable hydrogel system composed of gelatin, hydroxypehnylacetic acid and oxidized alginate, and loaded Vascular endothelial growth factor (VEGF). The oxidative reaction of horseradish peroxide (HRP) and hydrogen oxide (H2O2) catalyzed to prepare an injectable hydrogel. The HRP and H2O2 determined the hydrogel stiffness and the gelation ratio of injectable hydrogel. Chatacterization and materials properties were investigated based on microscope observation, gelation time, degradation rate and swelling ratio. In vitro studies of injectable hydrogels were evaluated by cytotoxicity, cell attachment and proliferation studies using Adipose Derived stem cells (ADSC) for evaluation of biocompatibility. |
| 저자 |
So-Ra Son1, Jun-Sang Bae2, Young-Ki Min3, Byong-Taek Lee4
|
| 소속 |
1Department of Regenerative Medicine, 2College of Medicine, 3Soonchunhyang Univ., 4InoBone company |
| 키워드 |
injectable hydrogel; oxidative reaction; VEGF
|
| E-Mail |
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