화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU))
권호 23권 2호
발표분야 포스터_생체재료
제목 Fabrication and Evaluation of Biological and Mechanical Properties of Hybrid PLCL 3D Porous Scaffold
초록 As human life expectation is prolonged by the development of medical technology, the importance of health became one of most important factors affecting the quality of life for the elderly. Consequently, tissue engineering attracts more attention to provide better resolutions for bone-related disease. Bone substitute grafts in 3D porous scaffolds can be on of suitable choice for this problem. In this study, we fabricate 3D porous scaffolds using poly(lactide-co-ε-caprolactone)(PLCL) synthesized by copolymerization of lactide and caprolactone monomers. PLCL is known to be excellent biocompatibility and biodegradability. The scaffolds are reinforced by ceramic particles to improve biological and mechanical properties of the scaffolds. The physical and chemical properties of the prepared scaffolds were examined using SEM, EDX, FT-IR, NMR, and GPC. Thermal property was analyzed using DSC. The biological functionality of the scaffolds was characterized by cell assays using osteoblast.
저자 박진우, 박선호, 이동규, 이지현, 홍재윤, 이우걸
소속 단국대
키워드 PLCL; Scaffold; CaP; Alendronate
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