| 학회 |
한국공업화학회 |
| 학술대회 |
2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
22권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Aligned PLCL nanosheets functionalized with RGD/IKVAV peptides for applications to neural tissue engineering |
| 초록 |
Many studies have been focused on the development of tissue engineering scaffold promoting neuronal cell behaviors. Herein, poly(lactide-co-ε-caprolactone) (PLCL) nanofiber sheets functionalized with M13 phages co-expressing RGD and IKVAV peptides (RGD/IKVAV-PLCL nanosheets) were fabricated by electrospinning. The physicochemical properties of RGD/IKVAV-PLCL nanosheets were characterized, and the cellular behaviors of HT22 mouse hippocampal cells on the nanosheets were investigated. Our results showed that HT22 hippocampal cell behaviors were remarkably promoted on the nanosheets. In conclusion, it is suggested that RGD/IKVAV-PLCL nanosheets can be promising candidates as neural tissue engineering scaffolds. |
| 저자 |
한동욱1, 강문성1, 신용철1, 송수진1, 이유빈1, 서희정1, 김춘태1, 오진우1, 현승휴2
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| 소속 |
1부산대, 2가고시마대 |
| 키워드 |
Nanofiber sheet; RGD; IKVAV; Electrospinning; Neural tissue engineering
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| E-Mail |
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