| 학회 | 한국화학공학회 |
| 학술대회 | 2020년 가을 (10/14 ~ 10/16, e-컨퍼런스) |
| 권호 | 26권 1호, p.704 |
| 발표분야 | 재료 |
| 제목 | Glutathione Modified Nitrogen-doped Carbon Dots for Dopamine Detection Based Fluorescence Analysis |
| 초록 | Abstract A novel water-soluble carbon dot nanoparticle for detecting dopamine with a simple and highly efficient method has been obtained. The N-doped carbon dot (NCDs) nanoparticles were synthesized by using a typical and facile hydrothermal route. The as-prepared NCDs were further passivated by attaching L-glutathione (GSH) though carbodiimide-activated coupling reaction on the NCDs surface (termed as GSH-NCDs). The GSH-NCDs particles showed an intriguing blue fluorescence with the emission wavelength at 440 nm when excited at 355 nm wavelength. The effect of different biomolecules towards the fluorescence of GSH-NCDs showed selective and sensitive DA sensing. For DA sensing, the limit of detection was calculated to be 1.01 nM, with a linear detection range of 0.02-10 µM. The fluorescence quenching was due to the interaction between GSH-NCDs and DA through GSH-DA electrostatic interaction. The as-designed sensing platform was successfully applied for biological sample analysis. Keywords: Glutathione, Carbon dots, Dopamine sensor, Fluorescent |
| 저자 | Wang Linlin1, Jayasmita Jana2, Hye Jin Lee2, Van Phuc Tran2, Ngoc Diem Huynh2, Yen Linh Thi Ngo2, 허승현2 |
| 소속 | 1울산대, 2Univ. of Ulsan |
| 키워드 | 화공재료 |
| 원문파일 | 초록 보기 |
