| 초록 |
Molecular imprinting is an effective method to obtain a synthetic material with a high selectivity for a target molecule. Therefore, in this study, a molecularly imprinted polymer (MIP) was synthesized via UV-polymerization using theophylline, methacrylic acid, polyester acrylate and 1-hydroxycyclohexyl acetophenone as a template, a functional monomer, a crosslinker and a photointiator, respectively. Two other MIPs were also synthesized by using acrylic acid or acryl amide as a functional monomer. Extraction of theophylline molecules from the MIPs was performed using the solution of chloroform/acetic acid (90/10 v/v). Binding performances of MIPs and non-imprinted polymers (NIPs) were compared. Selectivity analyses were carried out using a solution with theophylline and caffeine. All the binding tests for the MIPs were performed by checking the template concentration of the solution using a UV-visble spectrophotometer. The MIPs showed good rebinding characteristics and selectivity. |
