| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 가을 (10/06 ~ 10/08, 대구컨벤션센터(EXCO)) |
| 권호 |
40권 2호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Collagen/PCL Nanofibers Cross-linking and Characterization of Physical Properties as Irradiation Dose |
| 초록 |
Electrospun polymeric nanofibers have been extensively studied for biomedical materials because of their unique structures and relatively easy fabrication with biocompatible polymers. In this study, we developed collagen/PCL nanofibrous, hybrid nanofibrous scaffolds composed of poly(ε-caprolactone)(PCL) and type Ι collagen were cross-linked without the addition of a chemical cross-linking agent using 60Co γ-ray irradiation. The irradiation dose to effectively crosslink the collagen and PCL without chemical cross-linking agent was varied. After that, the surface morphology of scaffolds were analyzed by SEM, physicochemical properties were measured through FT-IR, water contact angle. As a result, by varying the dose, the PCL and collagen were increased surface wettability and mechanical properties by the cross-linking reaction. Therefore, its will be used to effective tissue engineered biomaterials by the improved biocompatibility and biological function. |
| 저자 |
임윤묵, 노영창, 안성준, 권희정, 박종석, 전성린, 윤세미, 김수정
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| 소속 |
첨단방사선(연) |
| 키워드 |
Collagen; PCL; Cross-linking; irradiation dose
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| E-Mail |
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