| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 봄 (04/10 ~ 04/11, 컨벤션 뷰로(대전)) |
| 권호 |
33권 1호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Fluorescent magnetic nanohybrids as multimodal imaging agents for human epithelial cancer detection |
| 초록 |
Cetuximab conjugated fluorescent magnetic nanohybrids (CET-FMNHs) were synthesized for detection of human epithelial cancer via magnetic resonance (MR) and optical imaging. Spherical FMNHs consist of MnFe2O4 magnetic nanocrystals encapsulated in pyrene-labeled poly (ε-caprolactone)-b-poly(methacrylic acid) as a surfactant prepared by a nano-emulsion method. FMNHs demonstrated excellent colloidal stability and biocompatibility for biomedical application. Antibody conjugated fluorescent magnetic nanohybrids (CET-FMNHs) served as effective agents for both magnetic resonance (MR) and fluorescence optical imaging of cancer cell lines. |
| 저자 |
양재문1, 임은경1, 이홍재2, 박요셉1, 이재민1, 이상천2, 서진석1, 허용민1, 함승주1
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| 소속 |
1연세대, 2요업기술원 |
| 키워드 |
fluorescent; magnetic; nanohybrids; imaging; cancer
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| E-Mail |
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