| 학회 |
한국고분자학회 |
| 학술대회 |
2018년 봄 (04/04 ~ 04/06, 대전컨벤션센터) |
| 권호 |
43권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 I |
| 제목 |
Effect of Ultrasound Stimulation Pattern on Bone Regeneration Using Alginate/Hyaluronic Acid Hydrogel |
| 초록 |
Ultrasound is described as an acoustic pressure wave, which can transfer mechanical energy into tissues and cause beneficial biochemical events at the cellular level. The use of ultrasound to promote bone regeneration was approved by the FDA for human application. In this study, we investigated the bone regeneration potential of injectable alginate (ALG)/hyaluronic acid (HA) mixture hydrogels with different ultrasound stimulation patterns. The extent of bone regeneration by the ALG/HA hydrogels with ultrasound stimulation was evaluated using a skull defect model of SD rats. The animal study result showed that the ultrasound stimulation groups regenerated more effectively bone regeneration than the groups without ultrasound stimulation. Bone regeneration was highly dependent by the applied ultrasound stimulation patterns. |
| 저자 |
김세현1, 이규진1, 김형규1, 주호1, 오세행2, 이진호1
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| 소속 |
1한남대, 2단국대 |
| 키워드 |
Bone regeneration; hydrogel; ultrasound; alginate; hyaluronic acid.
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| E-Mail |
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