| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 봄 (05/01 ~ 05/03, 부산 벡스코(BEXCO)) |
| 권호 |
23권 1호 |
| 발표분야 |
무기재료_포스터 |
| 제목 |
Gold and Upconversion Nanoparticle Hybrid Nanostructures for Cancer Therapy Mediated by Plasmon-enhanced Upconversion Emission |
| 초록 |
Lanthanide-doped upconversion nanoparticles (UCNP), with the unique ability to convert low-energy NIR radiation to high energy UV-vis light, represent promising agents.However, the intrinsically low quantum efficiency due to the presence of surface defects and small absorption cross-section have restricted their viable applications. The integration of localized surface plasmon resonance (LSPR) has been considered as a promising way to overcome this limitation.In this work, titanium-coated gold nanorods (Au NR@TiO2) were decorated with UCNP. This core@shell nanostructures revealed enhanced UCNP-derived UV emission due to the plasmonic properties of Au NR. In presence of UCNP, the emitted UV light was proposed to excite the TiO2 semiconductor and play a key role in the generation of cytotoxic singlet oxygen or reactive oxygen species. Hybrid nanostructures herein introduced are suggested to be a valuable addition in deep-range noninvasive cancer phototherapy studies. |
| 저자 |
유수빈1, 김동하1, 장도협2, 김세훈2, 이혁진1
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| 소속 |
1이화여자대, 2KIST |
| 키워드 |
Gold nanorod; Upconversion nanoparticle; photodynamic therapy; photothermal therapy
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| E-Mail |
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