| 학회 | 한국고분자학회 |
| 학술대회 | 2002년 가을 (10/11 ~ 10/12, 군산대학교) |
| 권호 | 27권 2호, p.232 |
| 발표분야 | 고분자 합성 |
| 제목 | Easy creation of various estrone recognition sites into silica particles by using a thermally reversible bond |
| 초록 | The mechanically stable materials having molecular recognition ability are of great interest due to their potential applications for chemical sensors, high performance chromatography as stationary phases, catalytic process, and membranes for separating toxic chemicals. Molecular imprinting has been widely used for the preparation of polymeric materials with specific binding property. For the imprinting, a template is complexed with a monomer either covalently or noncovalently, followed by the polymerization in the presence of a cross-linking agent. The removal of the template from the matrix generates a cavity with recognition ability, which is greatly influenced by rigidity of the matrix and the nature of a bond used for the template-monomer complexation. In this work, we used a thermally cleavable urethane bond for the preparation of a monomer-template complex. The advantages of this method are that the template can be removed by the simple thermal reaction and various functional groups can be introduced into a cavity. In addition, homogeneous dispersion of the template in the polymer matrix is expected. We prepared a silica monomer-template complex by the reaction of triethoxysilyl propylisocyanate with estrone. The reaction occurred between an isocyanato group of the monomer and a phenol moiety of estrone, forming a cleavable urethane bond. The quantitative analysis of estrone in a living body has been of great importance for preventing the breast cancer. |
| 저자 | 기창도, 장지영 |
| 소속 | 서울대 |
| 키워드 | estrone |
